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In addition, there can be thickening of the subepithelial

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Cough variant asthma (CVA) is characterised by eosinophilia in sputum,48 51 bronchoalveolar lavage (BAL) fluid,21,52 and in bronchial biopsy specimens.52,53 Up to 50% of patients with CVA have EB (table 1, fig 1), and the degree of eosinophilia is similar to asthma. In addition, there can be thickening of the subepithelial basement membrane, a feature of airway wall remodelling.53 The degree of remodelling is less than in classical asthma and raises the possibility that eosinophilic inflammation in CVA may be a precursor to the development of asthma. CVA progresses to typical asthma in 17 37% of cases.54 57.

He’s gone. The sound of a car starting. The Taco Bell wrappers clicking with the breeze from the fan.

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